Model of an Interdigitated Microsensor to Detect and Quantify Cells Flowing in a Test Chamber

نویسندگان

  • Elena Bianchi
  • Federica Boschetti
  • Gabriele. Dubini
  • Carlotta Guiducci
چکیده

A finite elements model of an interdigitated microsensor has been used to investigate the sensitivity of the sensor to the detection and the quantification of cells flowing in a test chamber. In particular the sensitivity of the sensor towards the geometry of sensors and the presence of a cell flowing through the channels was evaluated; several sensors topologies were considered in order to define proper guide-lines for the design of the microsensor.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of MTT and Trypan Blue assays for radiation-induced cell viability test in HepG2 cells

Background:  Cell viability is an important factor in radiation therapy and thus is a method to quantify the effect of the therapy. Materials and Methods: The viability of human hepatoma (HepG2) cells exposed to radiation was evaluated by both the MTT and Trypan blue assays. The cells were seeded on 96 well-plates at a density of 1 x 104 cells/well, incubated overnight, and irradiated with...

متن کامل

New Design of Mems piezoresistive pressure sensor

The electromechanical analysis of a piezoresistive pressure microsensor with a square-shaped diaphragm for low-pressure biomedical applications is presented. This analysis is developed through a novel model and a finite element method (FEM) model. A microsensor with a diaphragm 1000 „m length and with thickness=400 µm is studied. The electric response of this microsensor is obtained with applyi...

متن کامل

Analytical Approach for Vibration Analysis of a Microsensor with Two layers of Silicon and Piezoelectric based on MCST

The vibration analysis is an important step in the design and optimization of microsensors. In most of the cases, COMSOL software is employed to consider the size-dependency on the dynamic behavior in the MEMS sensors. In this paper, the Modified Couple Stress Theory (MCST) is used to capture the size effect on dynamic behavior in a microsensor with two layers of the silicon and piezoelectric. ...

متن کامل

Fabrication of Resistive E. coli Biosensor Based on ZnO Nanorods and Nanoparticles

In this paper, a biosensor has been fabricated using ZnO nanorods and nanoparticles to detect different concentrations of the E. coli bacteria. The innovation of this paper lies in design and fabrication of the resistive type E Coli bacteria sensor. To make this biosensors, printed circuit board based electrodes are designed and made in an interdigitated shape. Both hydrothermal and drop cast m...

متن کامل

Anti-angiogenic Effects of Metformin, an AMPK Activator, on Human Umbilical Vein Endothelial Cells and on Granulation Tissue in Rat

Objective(s)Metformin is well known for activation of AMP-activated protein kinase (AMPK). AMPK activation inhibits mammalian target of rapamycin (mTOR) as a key signaling process in cell proliferation. Recent epidemiological studies demonstrate that metformin lowers the risk for several types of cancer in diabetic patients. Concerning the critical role of angiogenesis in the incidence and prog...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2010